Indole-3-methanol

Takaitaccen Bayani:

Indole-3-methanol wani sabon nau'in metabolite ne na tsire-tsire na biyu wanda aka samar a cikin kayan lambu na cruciferous, wanda za'a iya fitar da shi daga kayan lambu na cruciferous (irin su broccoli, radish da farin kabeji).Indole-3-carbinol wani abu ne mai hana ƙwayar cuta.Indole-3-carbinol na iya hana faruwa da ci gaban ciwace-ciwace iri-iri.An yi amfani da Indole-3-methanol don ƙaddamar da poly lactic acid co glycolic acid (PLGA) don nazarin tasirin anticancer akan nono adenocarcinoma epithelial Kwayoyin (MCF7), colon adenocarcinoma epithelial cell (Caco2) da prostate ciwon daji epithelial Kwayoyin (PC3) in vitro.Hakanan ana amfani dashi azaman inducer na cytochrome P4501A (CYP1A).

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Bayani

Indole-3-methanol (I3C) yana kunna mai karɓa na hydrocarbon aromatic (AHR) kuma yana haifar da kama G1 cell cycle da apoptosis.Saboda haka, yana da yiwuwar maganin ciwon daji.Bugu da ƙari, yana haifar da estradiol metabolism ta hanyar ƙarfafa cytochrome P450 enzyme.Sabili da haka, ana ɗaukar I3C a matsayin maganin chemotherapy mai inganci don nau'ikan ciwon daji daban-daban, gami da kansar nono, kansar prostate, kansar hanji da cutar sankarar bargo.Indole-3-methanol na iya haifar da apoptosis na ƙwayoyin kansa kawai, wanda ba shi da lafiya kuma ba cytotoxic ga ƙwayoyin da ba ƙari ba.Saboda ingancinsa mai yawa, marasa guba da kaddarorin rigakafin cutar kansa, ana iya amfani da indole-3-methanol a matsayin ɗaya daga cikin masu neman rigakafin cutar kansa da magungunan magani.

Bayanin samfur

Saukewa: 700-06-1

Tsafta: ≥98%

Formula: C9H9NO

Formula Wt.Shafin: 147.17

Sunan Sinadari: INDOLE-3-CARBINOL

Synonym: Indole-3-carbinol, 99.5%; Indole-3-carbinol98%;(1H-Indol-3-yl)-methano;Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Wurin narkewa: 96-99 ° C

Wurin tafasa: 267.28°C

Bayyanar: Kashe-fari zuwa rawaya-orange crystalline foda ko flakes